Reproductive Effects of Disinfection By-products in Drinking Water

Project Timeline: 1/15/1999-5/14/2003

Sequoia Foundation conducted a series of epidemiologic analyses to estimate the strength of the associations between several disinfection by-products in drinking water and a range of parameters of reproductive function. The studies served to further characterize exposure to individual trihalomethanes (THMs) in the California Pregnancy Outcome Study.

For this project, Sequoia Foundation used distribution system modeling to estimate THM levels at or near homes of a subsample, which were then examined for associations between THMs and several male and female reproductive endpoints in the California Reproductive Health Study. A new prospective study of pregnancy outcomes and DBP exposure was also completed.